Cardiovascular risk in patients undergoing maintenance hemodialysis with Helixone® membrane: a multicenter randomized study.

Introduction: The high prevalence and incidence of atherosclerotic vascular complications, such as cardiovascular disease, remain the major cause of morbidity and mortality in patients undergoing dialysis.

Objectives: The aim of the study was to evaluate cardiovascular risk factors in patients dialyzed with a high‑flux polysulfone membrane (Helixone®) compared with those dialyzed with a low‑flux polysulfone membrane.

Patients And Methods: This was a crossover randomized study including 90 hemodialysis patients.

The clinicopathological determinants of native arteriovenous fistula failure in patients on maintenance hemodialysis.

Background: Progressive narrowing of the venous part of dialysis fistulae is caused by hemodynamic and inflammatory factors.

Objectives: The pathogenic and clinical determinants of deterioration of the functioning of arteriovenous fistulae in chronically hemodialyzed patients were evaluated.

Material And Methods: The hemodynamic parameters and the activity of inflammatory growth factors in the vessel wall of newly implanted fistulae were assessed and correlated with the clinical course of 34 hemodialyzed patients.