Binuclear V, Mo and Zn - hydroquinonate complexes: Synthesis, stability, oxidative activity and anticancer properties.

Since the discovery of the anticancer properties of cis-platin the road for the development of less toxic and more specific metal ion based anticancer drugs has opened. Based on the low toxicity of V, Mo and Zn metal ions, their binuclear hydroquinonate complexes have been synthesized and their biological activity towards their anticancer properties on various cancerous and non-cancerous cell lines has been evaluated. The new complexes of Zn with the ligands 2,5-bis((bis(pyridin-2-ylmethyl)amino)methyl)benzene-1,4-diol (Hbpymah) and 2,2'-(((2,5-dihydroxy-1,4-phenylene)bis(methylene))bis((carboxymethyl)ammoniumdiyl))diacetate (Hbicah) have been synthesized and characterized by X-ray crystallography in solid state and H NMR in aqueous solution.