Btp Proteins from Modulate the Lung Innate Immune Response to Infection by the Respiratory Route.

Although inhalation of infected aerosols is a frequent route for infection in humans, it rarely causes pulmonary clinical manifestations, suggesting a mild or nearly absent local inflammatory response. The goal of this study was to characterize the early innate immune response to intratracheal infection with in mice and to evaluate whether it is modulated by this pathogen. After infection with 10 CFU of , the pulmonary bacterial burden at 7 days post-infection (p.