Publications by authors named "Maria Smondrkova"
Nucleic Acids Res
February 2021
Article Synopsis
- - During homologous recombination, Dbl2 protein is crucial for positioning Fbh1, which is involved in dismantling Rad51-DNA filaments, and its absence (dbl2Δ) causes over 500 gene loci to be upregulated in the fungus Schizosaccharomyces pombe.
- - The misregulated genes due to dbl2 deletion are mainly linked to repetitive DNA sequences and overlap with various types of transcripts and retrotransposons, suggesting a specific pattern of gene regulation disrupted by the loss of Dbl2.
- - Cells lacking Dbl2 display increased nucleosome presence at transcription start sites and elevated levels of a specific histone modification (H3K9me2), indicating that Dbl2
