Publications by authors named "Maria Salbini"
Article Synopsis
- - Axitinib, a drug used for advanced kidney cancer, is being tested for effectiveness against glioblastoma, a severe brain tumor, and shows improved results when combined with other treatments
- - Research indicates that axitinib can lead to cellular senescence (aging) in both tumor and normal cells, but using the antioxidant N-Acetyl-L-Cysteine (NAC) may limit this effect in normal cells while preserving its anti-cancer properties
- - The study reveals that NAC combined with axitinib enhances blood vessel health in brain tumors and protects against liver damage from axitinib, suggesting a potential for better treatment outcomes with reduced side effects
Glioblastoma (GBM), the most malignant primary brain tumor in adults. Although not frequent, it has a relevant social impact because the peak incidence coincides with the age of professional maturity. A number of novel treatments have been proposed, yet clinical trials have been disappointing.
View Article and Find Full Text PDFIn this work we have compared two different sensing platforms for the detection of morphine as an example of a low molecular weight target analyte. For this, molecularly imprinted polymer nanoparticles (NanoMIP), synthesized with an affinity towards morphine, were attached to an electrochemical impedance spectroscopy (EIS) and a quartz crystal microbalance (QCM) sensor. Assay design, sensors fabrication, analyte sensitivity and specificity were performed using similar methods.
View Article and Find Full Text PDFOver the last few years, much attention has been paid to phytocannabinoids derived from Cannabis for their therapeutic potential. Δ-tetrahydrocannabinol (Δ-THC) and cannabidiol (CBD) are the most abundant compounds of the plant. Recently, novel phytocannabinoids, such as cannabidibutol (CBDB) and cannabidiphorol (CBDP), have been discovered.
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