Publications by authors named "Maria Safar-Boueri"
Front Immunol
January 2023
Article Synopsis
- - The study evaluates the use of Belatacept (Bela) in kidney transplant recipients undergoing early steroid withdrawal and avoiding calcineurin inhibitors, aiming to reduce nephrotoxicity and cardiovascular risk associated with long-term CNI use.
- - Out of 27 participants, those on the Bela+MPA regimen faced a high rate of biopsy-proven acute rejection, leading to the early closure of that group, while the Bela+low-dose Tac group showed improved kidney function compared to traditional Tac+MPA treatment.
- - Results suggest that maintaining low-dose Tac is essential to prevent rejection when transitioning to Bela in steroid-free regimens, particularly shortly after transplantation.
