Scoliosis in spinal muscular atrophy: is the preoperative magnetic resonance imaging necessary?

Purpose: To determine the prevalence of intraspinal alterations in scoliosis due to Spinal Muscular Atrophy (SMA).

Methods: Cross-sectional, observational, descriptive study. Fifty-six patients with SMA diagnosis required surgical treatment due to scoliosis.

Acute and sub-acute neurological toxicity in children treated for acute lymphoblastic leukemia.

Eighty percent of children with acute lymphoblastic leukemia (ALL) survive with current treatments. Neurotoxicity is an infrequent adverse event. We describe clinical presentations of neurological toxicity, phases of treatment when these adverse events were more frequent and patients ́ outcome.