Publications by authors named "Maria Rosaria Paravati"
A sedentary lifestyle associated with unregulated diets rich in high-calorie foods have contributed to the great prevalence of metabolic dysfunction-associated steatotic liver disease (MASLD) latterly, with up to 60% in the high-risk population and 25% in the general population. The absence of specific pharmacological strategies for this syndrome represents one of the major problems in the management of MASLD patients. Lifestyle interventions and adherence to a healthy diet are the main cornerstones of current therapies.
View Article and Find Full Text PDF() infection is a prevalent global health issue, associated with several gastrointestinal disorders, including gastritis, peptic ulcers, and gastric cancer. The landscape of treatment has evolved over the years, with increasing challenges due to antibiotic resistance and treatment failure. Traditional diagnostic methods, such as the urea breath test, stool antigen test, and endoscopy with biopsy, are commonly used in clinical practice.
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- Critically ill patients often experience a hyper-inflammatory response that leads to tissue damage and organ failure, with emerging research indicating the gut microbiota as a significant contributor to this response.
- Gut dysbiosis (an imbalance in gut bacteria) is linked to the development of systemic inflammatory response syndrome (SIRS) and multiple organ dysfunction syndrome (MODS), highlighting the importance of understanding gut health in critical care.
- Interventions like probiotics and immunonutrition show promise in mitigating systemic inflammation and improving patient outcomes in intensive care settings.
Liver transplantation (LT) is the treatment of choice for patients with cirrhosis, decompensated disease, acute liver failure, and hepatocellular carcinoma (HCC). In 3-25% of cases, an alarming problem is acute and chronic cellular rejection after LT, and this event can lead to the need for new transplantation or the death of the patient. On the other hand, gut microbiota is involved in several mechanisms sustaining the model of the "gut-liver axis".
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- Non-alcoholic fatty liver disease (NAFLD) is a widespread chronic liver condition affecting approximately 25.24% of the global population, driven by factors like insulin resistance and inflammation.
- The Mediterranean diet has been linked to positive outcomes for patients suffering from NAFLD, as shown by several clinical studies.
- This review focuses on the potential benefits of lycopene, a pigment found in fruits and vegetables, in managing and improving conditions related to NAFLD.