Neuroendocrine markers and psychological features in patients with irritable bowel syndrome.

Background And Aims: The key role of the brain-gut axis in the pathophysiology of irritable bowel syndrome (IBS) has been recognized. The aim of this study was to assess the possible association between IBS, neuroendocrine markers, and psychological features.

Methods: One hundred and twenty-five consecutive IBS patients and 105 healthy subjects were enrolled.