Clinical features and viral serologies in children with multiple sclerosis: a multinational observational study.

Background: The full spectrum of clinical manifestations and outcome, and the potential importance of regional or demographic features or viral triggers in paediatric multiple sclerosis (MS), has yet to be fully characterised. Our aim was to determine some of these characteristics in children with MS.

Methods: 137 children with MS and 96 control participants matched by age and geographical region were recruited in a multinational study.