Publications by authors named "Maria R Buenahora"

Article Synopsis
  • Spondyloarthritis (SpA) can lead to inflammatory bowel disease (IBD), with oral cavity changes often being the first clinical signs of IBD.
  • In a study with 80 SpA patients and 52 healthy controls, over 63% of the patients showed oral lesions, particularly gingivitis, which was significantly linked to IBD findings in the colon.
  • The research suggests that incorporating oral assessments into diagnostic processes for SpA could enhance early detection of IBD and improve patient care.
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Objective: Evaluate and compare the performance of autofluorescence, chemiluminescence, and clinical visual examination in the detection of oral potentially malignant disorders (OPMD), oral cancer (OC), and oropharyngeal cancer (OPC).

Materials And Methods: A systematic review with meta-analysis based on diagnostic test studies. A literature search was carried out in the MEDLINE and EMBASE databases through August 30, 2020.

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To evaluate the possible involvement of epigenetic modulation by HPV16-p16 in oral potentially malignant disorder (OPMD). We generated DNA-methylation profiles, according to p16 expression and HPV16 genotype (positive or negative), of OPMD samples and p16-HPV16 negative samples (used as control), using reduced-representation bisulphite sequencing (RRBS-Seq- Illumina) technology. Twelve samples, four for each group, as follows: 1) p16+ HPV16+; 2) p16+ HPV16-; 3) p16- HPV16-, were analysed in triplicate for DNA-methylation profiles.

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The increasing prevalence of human papilloma virus (HPV)-positive oral tumors can be considered an epidemic. Although the incidence of HPV cervical cancer is decreasing, the incidence of oral cavity and oropharyngeal cancers associated with HPV is increasing. The presence of certain HPV genotypes could be a predictor of future oral cancer lesions, although lesions associated with HPV could be less aggressive and exhibit a higher survival rate.

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