Publications by authors named "Maria Posada-Gonzalez"
Introduction: Antireflux surgery is commonly associated with significant recurrence and complication rates, and several surgical techniques have been proposed to minimize them. The aim of this study is to evaluate the results of a fundoplication with extensive dissection of the esophagogastric junction 1 and 3 years after the procedure.
Methods: Retrospective observational study including 178 patients with gastroesophageal reflux disease or hiatal hernia who underwent fundoplication with extensive dissection of the esophagogastric junction between 2015 and 2020.
Article Synopsis
- - The study compares adipose-derived mesenchymal stem cells (MSCs) from different fat sources (omentum and subcutaneous) in patients with morbid obesity, cancer, and healthy donors to assess their potential for clinical use.
- - Researchers found that while MSCs from obese and cancer patients have a similar mesenchymal phenotype and proliferation capacity as those from healthy donors, their differentiation potential and cytokine secretion vary significantly depending on the patient's pathology and fat source.
- - Specifically, omental MSCs from cancer patients exhibited higher anti-inflammatory properties but lower cell generation, whereas MSCs from both obesity and cancer patients showed alterations that could limit their therapeutic effectiveness.
Background: Up to 22% of the patients, after laparoscopic Roux-en-Y gastric bypass (LRYGB) can complain about gastroesophageal reflux disease (GERD) symptoms, there is little evidence about the most effective treatment of this situation.
Materials And Method: This video shows a laparoscopic reintervention after a LRYGB in a 42-year-old woman presenting with untreatable GERD. GERD was treated with maximum doses of PPIs with no effect on the symptoms; the patient had a 24-h pH and impedance manometry that showed an acid and non-acid reflux, and for that reason, we decided to perform a laparoscopic fundoplication.
This video shows a laparoscopic reintervention after an open, vertical banded gastroplasty in a 39-year-old woman presenting with untreatable GERD.
View Article and Find Full Text PDFArticle Synopsis
- - Parathyroid carcinoma is a rare type of cancer linked to conditions like hyperparathyroidism-jaw tumor syndrome, familial isolated primary hyperparathyroidism, and multiple endocrine neoplasia (MEN) types 1 and 2A.
- - A specific case is presented involving a 54-year-old man with MEN-2A, who has nonfunctional metastatic parathyroid carcinoma and a pheochromocytoma while lacking medullary thyroid carcinoma.
- - There have been very few documented instances of parathyroid carcinoma occurring in conjunction with the MEN-2A syndrome in existing literature.
Management of intrathoracic anastomotic leakage after esophagectomy by means of endoscopic stent insertion has gained wide acceptance as an alternative to surgical reintervention. Between January 2004 and March 2013 all patients who underwent esophagectomy at a German high-volume center for esophageal surgery were included in this retrospective study. The study comprises 356 patients.
View Article and Find Full Text PDFObjectives: Recurrent oesophageal carcinoma complicated by the development of a tracheo-oesophageal fistula is a crushing condition. In this situation, endoscopic double stenting may provide a quick and safe option for palliation.
Methods: The outcomes of patients who received endoscopic parallel stent implantation for tracheo-oesophageal fistula due to recurrent oesophageal cancer at a German tertiary referral hospital between 2006 and 2013 were reviewed in a retrospective case study.