Publications by authors named "Maria Pilar Sanchez Salas"
Article Synopsis
- The study examines the use of guselkumab for treating psoriasis in patients with a history of cancer, addressing the limited guidance available for such cases.
- A total of 20 patients were followed over 52 weeks, with high effectiveness rates seen (87.5% achieving a low psoriasis severity score) and a 100% survival rate, including those with active cancers.
- The findings suggest guselkumab is both effective and safe in this population, though the study is limited by its small sample size and retrospective design.*
Anti-programmed cell death (PD)-1 therapies in metastatic tumors have a high incidence of immune adverse events, including cutaneous manifestations such as vitiligo-like lesions. This side effect is associated with increased survival and it is a clinical marker of response to treatment. This case report is a graphic representation of the appearance of vitiligo-like lesions over in-transit metastases of malignant melanoma linked to a complete response to treatment with pembrolizumab.
View Article and Find Full Text PDFA 48-year-old man presented with a 4-month history of papular hyperkeratotic diffuse lesions on his trunk, arms, and neck that were highly pruritic (Figure 1). He also had "V"-shaped nicks in the nails, mucous white papules on his palate, and diffuse desquamation on the scalp. Abnormal laboratory values included elevated levels of uric acid and triglycerides.
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