Continuous monitoring of intrinsic PEEP based on expired CO kinetics: an experimental validation study.

Background: Quantification of intrinsic PEEP (PEEPi) has important implications for patients subjected to invasive mechanical ventilation. A new non-invasive breath-by-breath method (etCOD) for determination of PEEPi is evaluated.

Methods: In 12 mechanically ventilated pigs, dynamic hyperinflation was induced by interposing a resistance in the endotracheal tube.