Synopsis of recent research by authors named "Maria P Cosma"
- Maria P. Cosma's recent research explores the intricate relationship between genome organization, chromatin dynamics, and gene expression, utilizing advanced imaging techniques and deep learning methodologies to identify cellular heterogeneity and understand developmental processes.
- Key findings include the development of an artificial intelligence approach to detect nuclear signatures at nanoscale resolution and insights into how chromatin remodeling affects transcription during embryonic stem cell differentiation.
- Her studies also highlight the roles of specific proteins, such as NKX1-2 as a master regulator in early embryonic development, and the impact of transcription and epigenetic modifications on genomic organization, shedding light on the molecular underpinnings of cell fate transitions.