Publications by authors named "Maria Noel Marzano Rodrigues Petruzzi"

Article Synopsis
  • - Oral squamous cell carcinoma (OSCC) is a major type of oral cancer with a high and stable mortality rate, and the role of tumor-associated macrophages (TAMs) in its progression is significant yet not fully understood.
  • - M2 polarized TAMs are linked to poor clinical outcomes in OSCC, as their interactions with cancer cells promote tumor growth and aggressiveness through certain signaling pathways, reducing patient survival.
  • - The review highlights key interleukins and the Axl receptor's role in influencing TAM polarization to support OSCC progression, emphasizing the need for a deeper understanding of these molecular processes for improved targeted therapies and better patient prognoses.
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Article Synopsis
  • * Key findings indicate that low CD4+ counts, alcohol use, and female gender significantly increase the risk of oral candidiasis, while hairy leukoplakia is linked to factors like higher viral loads and smoking.
  • * The study concludes that immunodeficiency levels and lifestyle choices like smoking and drinking heighten the risk of oral infections in HIV-positive individuals, regardless of their antiretroviral treatment.
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The aim of the present study was to characterize, by means of SEM, primary endodontic infections and to correlate with clinical and radiographic findings. Twelve (12) human extracted teeth (19 roots) presenting primary endodontic infection were examined. SEM qualitative observations of bacterial and defense cells, their features and distribution within the root canal lumen and root dentine were recorded for association with clinical and radiographic tabled data.

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