Publications by authors named "Maria Nelli"
T are hematopoietic cells with unique features that provide intriguing insights into the interplay between innate and adaptive immunity. They express a combination of conventional dendritic cell (DC) and T-cell markers and are found in secondary lymphoid organs (SLOs), lungs and liver of naïve mice, as well as in human blood. When analyzed ex vivo, T can behave either as DCs or as T cells, depending on the provided stimuli.
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- T cells identified in naïve mice exhibit markers of both dendritic cells and conventional T-cells, showing unique functional properties.
- Using a specific mouse model, researchers discovered these cells in various tissues, confirming they have a distinctive gene signature.
- The study indicates that T cells increase in number during viral infections, suggesting a potential role in immune responses to infections and cancer.