Publications by authors named "Maria Natalia Gandur Quiroga"
The Impact of Fibroblast Growth Factor Receptor Alterations in Clinical Outcomes of Patients With Advanced Urothelial Carcinoma: Real-World Data From a Latin American Population.
Clin Genitourin Cancer
October 2024
Article Synopsis
- The study investigates the prevalence of FGFR mutations and fusions in Latino patients with metastatic urothelial carcinoma (mUC), finding these alterations in 17.9% of the analyzed population.
- Despite the presence of FGFR alterations, there was no significant difference in overall survival and time to treatment failure compared to patients without these mutations.
- The research also validates Bellmunt's prognostic model for predicting overall survival in this specific cohort of patients.
Use of concomitant proton pump inhibitors, statins or metformin in patients treated with pembrolizumab for metastatic urothelial carcinoma: data from the ARON-2 retrospective study.
Cancer Immunol Immunother
November 2023
Background: Concomitant medications may potentially affect the outcome of cancer patients. In this sub-analysis of the ARON-2 real-world study (NCT05290038), we aimed to assess the impact of concomitant use of proton pump inhibitors (PPI), statins, or metformin on outcome of patients with metastatic urothelial cancer (mUC) receiving second-line pembrolizumab.
Methods: We collected data from the hospital medical records of patients with mUC treated with pembrolizumab as second-line therapy at 87 institutions from 22 countries.
Teratomas are malign germ cell tumors composed of two or more tissue layers. When there is specific organ differentiation they are called mature teratoma. They rarely grow aggressively.
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