Gastric perforation and generalized peritonitis due to heterotopic pancreas, an unusual case report.

Introduction: Heterotopic pancreas is the presence of normal pancreatic tissue that is in an anatomical site different from the pancreas.

Case Report: Adolescent who was admitted to the emergency room due to intense, generalized abdominal pain, which did not go away with anything, was exacerbated with movements, 24 h later vomiting that occurred as soon as he ate food was added, and severe and progressive abdominal distention, reason for admission to the service of emergencies. He had no significant family or personal medical history.

Comparison of direct and indirect models of early induced acute lung injury.

Background: The animal experimental counterpart of human acute respiratory distress syndrome (ARDS) is acute lung injury (ALI). Most models of ALI involve reproducing the clinical risk factors associated with human ARDS, such as sepsis or acid aspiration; however, none of these models fully replicates human ARDS.

Aim: To compare different experimental animal models of ALI, based on direct or indirect mechanisms of lung injury, to characterize a model which more closely could reproduce the acute phase of human ARDS.

Effects of nebulized antithrombin and heparin on inflammatory and coagulation alterations in an acute lung injury model in rats.

Background: During acute respiratory distress syndrome, proinflammatory mediators inhibit natural anticoagulant factors, which alter the normal balance between coagulation and fibrinolysis leading to a procoagulant state. We hypothesize that pulmonary administration of anticoagulants might be beneficial to treat acute respiratory distress syndrome for their anticoagulant and antiinflammatory effects and reduce the risk of systemic bleeding.

Objectives: Our aim is to study the effects of nebulized antithrombin (AT) and combined AT and heparin in an animal model of acute lung injury.

Nebulized Heparin Attenuates Pulmonary Coagulopathy and Inflammation through Alveolar Macrophages in a Rat Model of Acute Lung Injury.

 Alveolar macrophages play a key role in the development and resolution of acute respiratory distress syndrome (ARDS), modulating the inflammatory response and the coagulation cascade in lungs. Anti-coagulants may be helpful in the treatment of ARDS. This study investigated the effects of nebulized heparin on the role of alveolar macrophages in limiting lung coagulation and inflammatory response in an animal model of acute lung injury (ALI).

[Information and information technology in health: contemporary health kaleidoscope].

This essay is based on the assumption that current practices and knowledge of Information and Information Technology in Health are unable to deal with the complexity of the health/disease/care processes and contemporary problems that must be overcome, curbing the expansion of the response capacity of the Brazilian State. It aims to further explore the understanding of the roots and determining factors behind these constraints, analyzing alternatives for confronting them that depend less on location-specific initiatives in the field of information and more - among others - on the adoption of new benchmarks, starting with the meaning and concept of Health. It identifies the existence of an 'information and information technology interfield' that arises from an epistemology based on a transdisciplinary approach, as well as the consolidation of a political and historical process of institutional construction, an area endowed with power and relevance: a political-epistemological interfield.