Household Transmission of SARS-CoV-2 and Long-term Immunity in Children: A Prospective Study in Northern Spain.

Background: The role of children in SARS-CoV-2 transmission and their immune response after infection have been profoundly discussed. Hereby, we analyze both aspects in a Spanish pediatric population.

Methods: Prospective, multicentre, longitudinal study performed from July 2020 to September 2021 in children up to 14 years old.

Low risk of bacteremia in otherwise healthy children presenting with fever and severe neutropenia.

We examined 785 placentas, including 51 from documented cases of congenital toxoplasmosis. Toxoplasma was detected in 16 placentas,including 1 in which congenital toxoplasmosis was ruled out. Placental screening had poor sensitivity (25%) but good specificity (99%), positive predictive value (93%), and negative predictive value (95%).