Publications by authors named "Maria Minerva Paz-Bribiesca"

Background: A heterogeneous geographic distribution of childhood acute lymphoblastic leukemia (ALL) cases has been described, possibly, related to the presence of different environmental factors. The aim of the present study was to explore the geographical distribution of childhood ALL cases in Greater Mexico City (GMC).

Methods: A population-based case-control study was conducted.

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Article Synopsis
  • - The study aimed to explore the relationship between parental age at conception and the risk of childhood acute leukaemia (AL) among Mexican children, given the high incidence of the disease in that population.
  • - A multicenter case-control approach was used, comparing children diagnosed with AL to matched controls, and applying statistical analysis to investigate the impacts of maternal and paternal ages on this risk.
  • - The findings revealed minimal associations between parental ages and childhood AL, though a higher risk for acute myeloid leukaemia (AML) was noted when mothers were 20-24 years old, and some association for acute lymphoblastic leukaemia (ALL) with younger mothers and fathers.
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In Mexico, due to the high rates of diabetes, overweight, and obesity, there has also been noted an increased newborn weight, which may be contributing to the elevated incidence rate of childhood acute leukemia (AL). We conducted a case-control study in public hospitals of Mexico City aimed to know whether a greater weight at birth is associated with a higher risk of developing leukemia. We included incident cases with acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML) diagnosed between 2010 and 2015.

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