Large orbital masses due to longstanding hydrogel retinal explants.

Aim: To describe the features of orbital masses occurring as a late complication of hydrogel retinal explants.

Patients And Methods: Retrospective review of patients presenting with orbital masses at decades after retinal surgery.

Results: Two patients with huge orbital masses are described, their presenting 25 and 28 years after retinal detachment repair with expansile hydrogel explants.

Progressive Necrotizing Ocular Surface Disease, Despite Immunosuppression.

A 60-year-old man was referred with 2 years of left conjunctivitis that persisted despite antibiotic and systemic corticosteroid therapy. The severity and extent of surface disease had increased slowly after prior dacryocystorhinostomy. Subsequent conjunctival biopsies demonstrated granulomas with patchy necrosis but no evidence of malignancy or organisms; systemic screening for sarcoidosis and tuberculosis was negative.

A novel KRAS mutation in metastasic conjunctival melanoma: a case report and literature review.

Conjunctival melanoma is a rare disease, and little is known about its molecular background. Here, we present the case of a 48-year-old patient with conjunctival melanoma and metachronic lymph node and skin metastasis with KRAS p.K117Y mutation in exon 4 in all the lesions.