Morphological aspects as prognostic factors in malignant mesothelioma: a study of 58 cases.

Objective: Various markers have shown promise as diagnostic markers and prognostic predictors in malignant mesothelioma (MM).

Methods: Through morphometric and immunological studies of markers in stromal components (calretinin, CEA, Leu-M1 and thrombomodulin) and nuclear components (p53 and Ki-67), we evaluated post-diagnosis survival in 58 patients with MM.

Results: The histologic pattern of the MM was typical in 50 cases and atypical in 8.