Publications by authors named "Maria Magdalena Gurzun"

Article Synopsis
  • Non-functioning adrenal incidentalomas (NFAIs) are associated with a higher risk of glucose profile issues, especially type 2 diabetes mellitus (T2DM), though clear links to Cushing's syndrome aren't fully established.
  • A comprehensive literature review analyzed 37 studies involving over 17,000 individuals, finding T2DM prevalence in NFAIs with mild autonomous cortisol secretion (MACS) ranged from 12% to 44%, with some studies showing rates as high as 45.2%.
  • Comparisons between NFAIs and non-tumor controls indicated increased T2DM rates in NFAIs, and while some studies examined Cushing's syndrome, results regarding glucose profile anomalies were inconsistent.
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Article Synopsis
  • - Magnesium (Mg) is a crucial nutrient that acts as a cofactor in more than 600 enzymatic reactions essential for various physiological functions, such as protein synthesis, DNA repair, and regulating cardiac rhythm.
  • - A review of 30 clinical studies from January 2019 to April 2024 explored the link between daily magnesium intake (DMI) and metabolic traits, especially focusing on type 2 diabetes mellitus (DM), revealing that many diabetic patients have lower DMI levels.
  • - Findings indicated that insufficient DMI is correlated with an increased risk of developing DM, and there may be a linear relationship between DMI and DM control at specific levels, highlighting the importance of dietary magnesium management for diabetics.
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Background: Structural right ventricular (RV) abnormalities are present in a substantial proportion of patients with hypertrophic cardiomyopathy (HCM), but the trigger for RV hypertrophy remains unclear. The aim of this study was to assess the relationship between RV and left ventricular (LV) remodeling and the impact of biventricular involvement on clinical status in this setting.

Methods: Ninety-nine patients with HCM and 30 normal subjects with a similar age and gender distribution were prospectively enrolled.

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Mitral regurgitation (MR) represents the second most frequent valvular heart disease. The appropriate management of organic MR remains unclear in many aspects, especially in several specific clinical scenarios. This review aims to discuss the current guideline recommendations regarding the management of organic MR, while highlighting the controversial aspects encountered in daily clinical practice.

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There is a long-standing debate between proponents of routine intra-operative echo and those who want it restricted to selected groups of patients (such as those undergoing valve repair or correction of congenital abnormalities). We present a case where routine transesophageal echocardiography (TEE) identified completely unexpected pathology, with implications for the postoperative follow-up and for patient outcomes. A 64-year-old male, with a history of surgical repair of coarctation of the aorta in childhood, was admitted for elective valve replacement for severe aortic stenosis (AS).

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Background: Appropriateness of use criteria (AUC) for transthoracic echocardiography (TTE) have been developed by American cardiology associations to help avoid unnecessary scans by formalizing indications for imaging. There are 98 indications classified as either appropriate (A), inappropriate (I), or uncertain (U). AUC may allow better targeting of limited resources, but they have not been tested systematically outside the USA.

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Purpose: Left ventricular hypertrophy (LVH) is as an independent risk factor. Discrepancies were reported between LV mass (LVM) estimated by echocardiography and electrocardiography (ECG) findings. We hypothesized that QRS voltage criteria may reflect not only anatomical changes (LVM) but also changes in LV function and we tested the relationship between QRS voltage and echocardiographic parameters of LV function in patients (pts) with different types of LVH.

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