Publications by authors named "Maria M Sanchez-Chaparro"
Article Synopsis
- Hereditary breast and ovarian cancer (HBOC) syndrome is primarily linked to mutations in specific genes, with focus on the genetic variations in 3'UTR regions that affect microRNA binding and regulation.
- A study involving blood samples from 50 HBOC patients and 50 controls identified nine polymorphisms in these regions, with three variants significantly increasing the risk of developing HBOC.
- The findings suggest that these genetic variants can influence microRNA binding, highlighting their role in the development of HBOC.
Article Synopsis
- This study investigates the prevalence of a specific oral infection linked to gastrointestinal disorders in patients with periodontitis, highlighting that the infection is more common in developing countries.
- Researchers analyzed dental plaque samples from 38 patients, with 60.5% testing positive for the infection-associated genes, indicating a significant correlation between periodontal issues and the oral infection.
- The findings suggest that improving oral hygiene and targeting the infection could help manage the progression of periodontal disease.
is an opportunistic fungus present in humid environments, whose natural environment is in soil, hay and compost. It is a frequent contaminant in the clinical laboratory. Because of this, the fungus is often inhaled, affecting those with an underlying pulmonary disease or immune deficiency.
View Article and Find Full Text PDFThe enzyme myo-Inositol oxygenase (MIOX) is also termed ALDRL6. It is a kidney-specific member of the aldo-keto reductase family. MIOX catalyzes the first reaction involved in the myo-inositol metabolism signaling pathway and is fully expressed in mammalian tissues.
View Article and Find Full Text PDFAssociation of the polymorphism 12109g>A from the REN gene as a risk factor for preterm birth.
J Renin Angiotensin Aldosterone Syst
April 2017
Introduction: Preterm birth is the most important cause of neonatal mortality and morbidity. It is a multifactorial disease with different etiologies, including genetic factors. Genetic variability is represented by single nucleotide polymorphisms (SNPs) in genes of proteins involved in the contractile activity.
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