Publications by authors named "Maria M Bontemps-Gracz"
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Synopsis of recent research by authors named "Maria M Bontemps-Gracz"
Maria M Bontemps-Gracz's research primarily focuses on developing new anticancer agents that can effectively target multidrug-resistant (MDR) tumor cells by synthesizing various chemical compounds, including 7-oxo-7H-naphthoquinoline derivatives and acridine cytostatics.
Her findings demonstrate that specific structural modifications in these compounds significantly enhance their cytotoxic activity against resistant cell lines, thereby overcoming common challenges in chemotherapy.
Bontemps-Gracz also reviews strategies for addressing the mechanisms of multidrug resistance, highlighting the crucial role of efflux pumps like P-glycoprotein and the potential of novel inhibitors in circumventing these barriers in cancer treatment.
