Assessment of pH Value and Release of Calcium Ions in Calcium Silicate Cements: An In Vitro Comparative Study.

Unlabelled: The goal of this study was to evaluate the pH and the release of calcium from four calcium-silicate-based cements.

Methods: Four materials were tested (ProClinic MTA; Angelus MTA; ProRoot MTA; Biodentine). The palatal canal root of acrylic upper molars was filled with each cement.

Chaotic parameters from fluorescence spectra to resolve fraudulent mixtures of fresh and expired protected designation of origin extra virgin olive oils.

One of the most profitable products from the Mediterranean basin is extra virgin olive oil (EVOO), and, therefore, some of them have protected designation of origin (PDO) labels. In order to prevent fraudulent practices, a method to quantify adulterants has been developed. 459 binary blends composed of PDO EVOO in date (Saqura, Oleoestepa, and Duque de Baena) mixed with expired PDO EVOO (Quinta do Vallouto, Señorío de Segura, and Planeta) to serve as adulterants (<17%) have been analyzed.

2-Deoxy-D-glucose cooperates with arsenic trioxide to induce apoptosis in leukemia cells: involvement of IGF-1R-regulated Akt/mTOR, MEK/ERK and LKB-1/AMPK signaling pathways.

While the anti-tumor efficacy of 2-deoxy-D-glucose (2-DG) is normally low in monotherapy, it may represent a valuable radio- and chemo-sensitizing agent. We here demonstrate that 2-10 mM 2-DG cooperates with arsenic trioxide (ATO) and other antitumor drugs to induce apoptosis in human myeloid leukemia cell lines. Using ATO and HL60 as drug and cell models, respectively, we observed that 2-DG/ATO combination activates the mitochondrial apoptotic pathway, as indicated by Bid-, and Bax-regulated cytochrome c and Omi/HtrA2 release, XIAP down-regulation, and caspase-9/-3 pathway activation.