Publications by authors named "Maria Luisa de-Castro-Parga"

Article Synopsis
  • A study was done to see if a type of screening test called FIT was better than the usual procedure, colonoscopy, for first-degree relatives of people with colorectal cancer.
  • The researchers wanted to know if more people would agree to take the FIT test compared to colonoscopy and if both tests would find the same number of serious issues.
  • The study was planned to involve many people over several years but had to stop early because it wasn't looking like it would have good results, even though they still gathered data for two years after.
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Background: Even if the use of stent as bridge to surgery (BTS) for obstructive colon cancer was described long ago, there is still much controversy on their use. Patient recovery before surgery and colonic desobstruction are just some of the reasons to defend this management that can be found in several available articles.

Methods: This is a single-center, retrospective cohort study, including patients with obstructive colon cancer treated between 2010 and 2020.

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Article Synopsis
  • Adalimumab is a biological therapy for chronic inflammatory diseases, and there are increasing biosimilars available, necessitating evidence on the safety and efficacy of switching between reference adalimumab and its biosimilars.
  • A systematic review of studies from 2004 to 2021 identified 21 relevant studies involving 2,802 patients across various conditions, including rheumatoid arthritis, psoriasis, and inflammatory bowel disease.
  • The findings indicate that switching between reference adalimumab and biosimilars does not significantly affect efficacy, safety, or immunogenicity, suggesting similar outcomes for different adalimumab biosimilars and potential applicability to other rheumatic diseases.
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Introduction: The management of patients with inflammatory bowel disease (IBD) is associated with a significant use of healthcare resources. In 2009, a digestive diseases nursing consultation, with availability of health telematic media was created in our hospital (CHUVI). The important activity performed in this area encouraged us to quantify the cost savings for the care health system.

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