Osteogenic cells transfer improving root coverage: A randomized clinical trial.

Background And Objective: The aim of this interventional, parallel-assignment, single-blinded, randomized, efficacy study was to investigate the efficacy of the treatment of gingival recessions by osteogenic cell transfer. This is the first randomized clinical trial of this nature.

Material And Methods: Treatment of Miller class I or II gingival recessions >4 mm was randomly defined by casual sorting and performed by newly forming bone graft (NFBG) and coronally advanced flap (CAF) or subepithelial connective tissue graft (SCTG) and CAF (control).

Bone demineralization with citric acid enhances adhesion and spreading of preosteoblasts.

Background: Previous studies have demonstrated that bone demineralization can improve consolidation in bone grafts. The biologic mechanisms underlying this phenomenon remain unclear.

Methods: Twelve adult male guinea pigs were used in this experiment.