Publications by authors named "Maria Lotti Enrico"
Article Synopsis
- The study investigates when it's best to start oral anticoagulants after an ischemic stroke caused by atrial fibrillation, particularly focusing on patients who received thrombolysis or thrombectomy.
- It combines data from two studies conducted between 2012 and 2016, analyzing patients treated with either Vitamin K antagonists or non-vitamin K oral anticoagulants for secondary stroke prevention.
- Among 2159 patients included, the timing for starting anticoagulants was similar for those treated with reperfusion therapies and those not treated, with low rates of stroke or bleeding complications observed within 90 days.
The association between preceding treatment with antiplatelet agents (APs), vitamin K antagonists (VKAs) or direct oral anticoagulants (DOACs) and mortality after intracerebral hemorrhage (ICH) remains unclear. The aim of this multicenter, prospective cohort study was to assess the risk for death after ICH in consecutive patients who were on treatment with APs, VKAs, DOACs, or no antithrombotic agent. The primary outcome was in-hospital death by day 30.
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- * Researchers analyzed data from 1,810 patients, discovering that 20% underwent this bridging therapy, and found that bridged patients had worse outcomes, with a higher rate of ischemic events and major bleeding.
- * The results indicate that bridging therapy significantly raises the risk of early complications compared to patients who did not receive it, prompting a reevaluation of its common use in clinical practice.
Article Synopsis
- A study examined clinical, neuroimaging, and laboratory characteristics of 102 Italian patients diagnosed with reversible cerebral vasoconstriction syndrome, focusing on differences between idiopathic and secondary cases.
- The majority of patients (83.3% females) reported thunderclap headaches, which were more common in idiopathic cases and occurred at an older average age compared to secondary cases.
- Findings suggest that the clinical features and possible causes of reversible cerebral vasoconstriction syndrome might differ slightly from previous studies, indicating a need for further research.