External Validation of SAFE Score to Predict Atrial Fibrillation Diagnosis after Ischemic Stroke: A Retrospective Multicenter Study.

Introduction: The screening for atrial fibrillation (AF) scale (SAFE score) was recently developed to provide a prediction of the diagnosis of AF after an ischemic stroke. It includes 7 items: ≥ 65 years, bronchopathy, thyroid disease, cortical location of stroke, intracranial large vessel occlusion, NT-ProBNP ≥250 pg/mL, and left atrial enlargement. In the internal validation, a good performance was obtained, with an = 0.

Upregulation of Heat-Shock Protein (hsp)-27 in a Patient with Heterozygous SPG11 c.1951C>T and SYNJ1 c.2614G>T Mutations Causing Clinical Spastic Paraplegia.

We report a 49-year-old patient suffering from spastic paraplegia with a novel heterozygous mutation and analyzed the levels of heat shock proteins (hsp)-27, dopamine (DA), and its metabolites in their cerebrospinal fluid (CSF). The hsp27 protein concentration in the patient's CSF was assayed by an ELISA kit, while DA levels and its metabolites in the CSF, 3,4-dihydroxyphenylacetic acid (DOPAC), Cys-DA, and Cys-DOPA were measured by HPLC. Whole exome sequencing demonstrated SPG-11 c.

Domestic Dogs as Sentinels for West Nile Virus but not Aedes-borne Flaviviruses, Mexico.

We tested 294 domestic pet dogs in Mexico for neutralizing antibodies for mosquito-borne flaviviruses. We found high (42.6%) exposure to West Nile virus in Reynosa (northern Mexico) and low (1.

Vertebrate-Aedes aegypti and Culex quinquefasciatus (Diptera)-arbovirus transmission networks: Non-human feeding revealed by meta-barcoding and next-generation sequencing.

Background: Aedes aegypti mosquito-borne viruses including Zika (ZIKV), dengue (DENV), yellow fever (YFV), and chikungunya (CHIKV) have emerged and re-emerged globally, resulting in an elevated burden of human disease. Aedes aegypti is found worldwide in tropical, sub-tropical, and temperate areas. The characterization of mosquito blood meals is essential to understand the transmission dynamics of mosquito-vectored pathogens.

[Evolution and treatment of storm cytoquine syndrome associated to SARS-CoV-2 infection among octogenarians].

Introduction: Cytokine storm syndrome (CTS) is a serious complication of patients with SARS-CoV-2 infection. Treatment and evolution in octogenarians are not well defined. Our objective is to describe its clinical characteristics, the treatments and its clinical evolution.

Healthcare students' personality traits and competence-based learning methodologies.

The European Higher Education Area was implemented more than a decade ago with the aim of improving internationally the competitiveness of European university education putting the spotlight on skills and competence development (and not only on knowledge acquisition). This work intends to analyze the impact of competence-based teaching methodologies on university students, as well as to contribute to the study of the individual personality traits differences regarding this impact. For this, a descriptive, quantitative, cross-sectional study was conducted with a non-randomised sample of university students.

Grieving for Job Loss and Its Relation to the Employability of Older Jobseekers.

Loss of employment is an experience that is lived and interpreted differently depending on a series of individual variables, including the psychological resources available to the affected person as well as their perception of their degree of employability. Losing one's job can be one of the most painful and traumatic events a person has to withstand. Following a dismissal, the worker needs to overcome a period of emotional adaptation to the loss.

Biochemical and Biophysical Characterization of the Enolase from .

Enolase, which catalyses the conversion of 2-phospho-D-glycerate to phosphoenolpyruvate, is an important enzyme in the classic glycolysis pathway in cells. Enolase is highly conserved in organisms from bacteria to humans, indicating its importance in cells. Thus, enolase is a good target for developing new drugs.

Engagement, Passion and Meaning of Work as Modulating Variables in Nursing: A Theoretical Analysis.

Nurses are continuously exposed to stressors and psychological and physical risks that can negatively influence their daily work. These adverse psychosocial circumstances, accompanied by the poor self-perception of health, well-being, and quality of life, may trigger burnout. The positive psychology approach pursues a growth of passion at work, increased job satisfaction, and occupational health, both mental and physical, for the optimal performance of the nursing role.

Risk factors for mental workload: influence of the working environment, cardiovascular health and lifestyle. A cross-sectional study.

Objectives: Mental workload is a condition which can negatively influence the overall health of workers. In this study, we aimed to investigate the risk factors for the onset of mental workload, including working conditions, cardiovascular comorbidities and lifestyle habits, in a working population.

Methods: This is a cross-sectional study including 408 workers from a risk prevention service of small/medium companies in Murcia (Spain).

What Does Work Signify for Those in Search of Labor? Meaning of Work for the Unemployed Who Attend an Employee Orientation Program.

Work is one of the most important areas in people's lives. This is highly related to the meaning of work people possess and the social culture that surrounds them. However, unemployment stands out as a major social phenomenon of the 21st century of concern for governments, institutions, and professionals, generating the need to reflect, among other issues, on the processes that favor and keep the person in the situation of unemployment, and to think about the real effects of the measures aimed at supporting and guiding the unemployed.

Organisational Justice, Burnout, and Engagement in University Students: A Comparison between Stressful Aspects of Labour and University Organisation.

Burnout, engagement, and organisational justice concepts are usually studied in the context of labour organisations, but not in universities. For this, the objective of this research is to identify the students' empirically evidenced relationships in the employment context, such as levels of organisational justice, stress indicators, burnout and work commitment. On the other hand, engagement is analysed as a mediating variable that explains the relationship between organisational justice and burnout.

Psychological Coping with Job Loss. Empirical Study to Contribute to the Development of Unemployed People.

Having a job is an essential part of people's development. Unemployment, on the contrary, is one of the most frustrating experiences of life with greater psychological consequences for people's lives. In this sense, psychology has contributed to an increase in knowledge about the personal and social experience of unemployment.

[Pheochromocytoma giant cystic: a case report].

The giant cystic pheochromocytoma is a rare adrenal tumor in the predominantly asymptomatic course; so many cases are not diagnosed until the time of surgery. The simple mobilization of the tumor is associated with the passage to the blood of large amounts of catecholamines and high morbidity and mortality. So the surgery itself and perioperative management are a huge challenge.

[Burden, empathy, and resilience in dependent people caregivers].

Objective: To analyse the differences in perceived burden between family caregivers who are users of patient associations and those who are not; to assess the relationship between burden, resilience, and empathy levels.

Method: Retrospective ex post facto study of two groups, one of them quasi control. The sample was composed of 155 informal caregivers (28 men and 155 women); 109 of them were users of patient relatives' associations and 46 were not.

Multi-spectral imaging for the estimation of shooting distances.

Multispectral images of clothing targets shot at seven different distances (from 10 to 220cm) were recorded at 18 specific wavelengths in the 400-1000nm range to visualize the gunshot residue (GSR) pattern. Principal component analysis (PCA) showed that the use of violet-blue wavelengths (430, 450 and 470nm) provided the largest contrast between the GSR particles and the white cotton fabric. Then, the correlation between the amount of GSR particles on clothing targets and the shooting distance was studied.

Investigation of the use of luminescent markers as gunshot residue indicators.

The addition of luminescent markers into ammunition cartridges is an appealing proposal to achieve a greater individual identification of the ammunition. The lanthanide elements present in these luminescent materials act as characteristic chemical markers that, also, offer the great benefit of making gunshot residues (GSR) collection easier. Although the use of luminescent markers offers numerous advantages, and can be a reliable future option in the cartridge ammunition market, little or nothing is known about the interaction of the marker with the ammunition compounds after the shot.

Comparison of halogen bonding networks with Ru(ii) complexes and analysis of the influence of the XB interactions on their reactivity.

Coordination compounds of formula [Ru(Cl)(CNR)] are interesting building blocks for the preparation of halogen bonding supramolecular networks, since the chloride ligand is a good XB acceptor. When using I as the XB donor, an unexpected reaction on the ruthenium coordination sphere happens where the chloride ligands are substituted by iodides. The isolation of several intermediates with different substitution degrees and showing XB interactions in a solid state network evidenced the clear influence of the XB species in this unusual reaction process.

Novel protein interactions with an actin homolog (MreB) of Helicobacter pylori determined by bacterial two-hybrid system.

The bacterium Helicobacter pylori infects more than 50% of the world population and causes several gastroduodenal diseases, including gastric cancer. Nevertheless, we still need to explore some protein interactions that may be involved in pathogenesis. MreB, an actin homolog, showed some special characteristics in previous studies, indicating that it could have different functions.

An exploratory study of the potential of LIBS for visualizing gunshot residue patterns.

The study of gunshot residue (GSR) patterns can assist in the reconstruction of shooting incidences. Currently, there is a real need of methods capable of furnishing simultaneous elemental analysis with higher specificity for the GSR pattern visualization. Laser-Induced Breakdown Spectroscopy (LIBS) provides a multi-elemental analysis of the sample, requiring very small amounts of material and no sample preparation.