The bone and mineral disorder of children undergoing chronic peritoneal dialysis.

The mineral and bone disorder of chronic kidney disease remains a challenging complication in pediatric end-stage renal disease. Here, we assessed symptoms, risk factors and management of this disorder in 890 children and adolescents from 24 countries reported to the International Pediatric Peritoneal Dialysis Network Registry. Signs of this disease were most common in North American patients.

[Simvastatin therapy and effect on hiperlipidemia and vascular status in nephrotic children with sustained dyslipidemia].

Unlabelled: Dyslipidemia is common in nephrotic children and persistent lipid abnormalities are risk factor of late vascular complications. The aim of the study was evaluation of efficacy and safety of 12-months simvastatin therapy in nephrotic children with lipid profile abnormalities present despite clinical remission lasting for at least 8 weeks, including ultrasonographic assessment of carotid and femoral arteries.

Material And Methods: Overall 52 children (40 steroid-dependent and 12 steroid-resistant) were initially introduced to the study and 29 of them were treated with simvastatin.

Application of novel dual wave meal bolus and its impact on glycated hemoglobin A1c level in children with type 1 diabetes.

Background: An insulin pump is an advanced technology offering new options of bolus - normal (N), dual wave (D-W) or square wave (S-W) bolus to deliver mealtime insulin.

Objectives: To assess the impact of D-W/S-W boluses on metabolic control (glycated haemoglobin A1c, HbA1c) and to estimate the paediatric patients compliance with implementation of this system in daily practice.

Methods: The cross-sectional study included 499 records of patients aged 0-18 yr.

Age-dependent basal insulin patterns in children with type 1 diabetes treated with continuous subcutaneous insulin infusion.

Aims: Identifying age-dependent basal rates in type 1 diabetic children treated with continuous subcutaneous insulin infusion (CSII).

Methods: CSII-treated children with type 1 diabetes exhibiting insulin requirement > 0.5 U/kg and glycated haemoglobin (HbA1c) < 8%.

Insulin requirement in preschoolers treated with insulin pumps at the onset of type 1 diabetes mellitus.

The Aim: The aim of this study is to analyze changes in the basal insulin requirement in preschoolers treated with insulin pump at the onset of T1DM, using system to calculate meal time insulin.

Methods: 58 children (31 girls) under 6 years (mean age 3.3 +/- 1.

Basal insulin and total daily insulin dose in children with type 1 diabetes using insulin pumps.

Objective: To assess the contribution of basal insulin to the total daily dose (CBITDD) and to identify the determinant factors in children with type 1 diabetes mellitus.

Study Design: Cross-sectional study in which the basal insulin requirement was established based on a memory read-out of insulin delivery from pumps. Factors such as glycated haemoglobin A1c (HbA1c), fasting C-peptide, standard deviation score of body mass index (sdsBMI) and demographic data were determined during routine hospital visits.

Sustained metabolic control and low rates of severe hypoglycaemic episodes in preschool diabetic children treated with continuous subcutaneous insulin infusion.

Aim: To evaluate the safety and efficacy of continuous subcutaneous insulin infusion (CSII) in children under 7 years of age.

Methods: One hundred and ten children, aged 0.9-7 years, who had received CSII therapy for at least 6 months, were studied for 237 patient-years by a retrospective chart review.

[The evolution of insulin therapy and new insight into nutrition recommendations for individuals with diabetes].

The dietary guideline has undergone change during the last decades. It has been done by the introduction of new insulin therapy methods, also by the numerous epidemiological studies which have documented the influence of eating habits on macro-vascular diseases, obesity and type 2 diabetes. The Glycemic Index (GI) and Glycemic Load (GL) play a pivotal role in carbohydrate classification and for food choice by diabetic patients.

[Evaluation of arterial intima-media thickness (IMT) in children with idiopathic nephrotic syndrome--preliminary report].

Unlabelled: One the complications of idiopathic nephrotic syndrome (i.n.s.

[Guidelines concerning insulin dosage in children and adolescents with type 1 diabetes on continuous subcutaneous insulin infusion].

The treatment of diabetes mellitus with a continuous subcutaneous insulin infusion (CSII) has become very popular and is well accepted by diabetic patients. Pump therapy mimics the physiological insulin secretion and has been shown to be a safe and effective method of insulin administration alternative to the method of multiple injections. Continuous insulin infusion provides greater flexibility in the timing of meals and snacks with higher treatment satisfaction.

[The role of 2,3-DPG in nerve conduction of children with type 1 diabetes].

Background: Neuropathy is one of the chronic complications of diabetes, and it is uncommon in children and adolescents. It can be recognized in a short period after the onset of diabetes and not always is connected with poor metabolic control. Hypoxia is considered as one from greatest factors diabetic neuropathy and oxygen transport to tissue partially depends on the diphosphoglycerate (2,3 DPG) concentration.

Memory of insulin pumps and their record as a source of information about insulin therapy in children and adolescents with type 1 diabetes.

Background: This study was designed to provide information regarding basal and bolus insulin dosage in children and adolescents using continuous subcutaneous insulin infusion (CSII) and to evaluate the safety and efficacy of the CSII method in youths.

Patients And Methods: Data from 100 patients (1.6-18 years old) were collected during scheduled visits in an outpatient clinic.

[Metabolic control in young children with type 1 diabetes treated with continuous subcutaneous insulin infusion (insulin pump)].

Unlabelled: Intensive insulin therapy is a method of choice in the management of patients with type 1 diabetes. Its administration in the youngest children is limited by little or no acceptance of multiple injections and a typical fear of needles and syringes. In recent years more and more frequently the method of multiple daily injections (MDI) of insulin is being replaced by the method of continuous subcutaneous insulin infusion (CSII) even in the youngest children.