Topical continuous use of Lippia sidoides Cham. essential oil induces cutaneous inflammatory response, but does not delay wound healing process.

Ethnopharmacological Relevance: The essential oil of Lippia sidoides (EOLS) has been used in Brazilian folk medicine as a topical antiseptic agent in skin for treatment of wounds and superficial infections of the body. The aim of this study was to investigate the effects of EOLS on intact and damaged skin, including its action on expression of mediators, COX-2 and VEGF, involved in healing full-thickness cutaneous lesions in vivo.

Material And Methods: EOLS was analyzed chemically and used at different concentrations to dose-response experiments in skin mice.

In vivo topical anti-inflammatory and wound healing activities of the fixed oil of Caryocar coriaceum Wittm. seeds.

Ethnopharmacological Relevance: Caryocar coriaceum Wittm. (Caryocaraceae), popularly known as pequi, is important source of food and used in the folk medicine as wound healing, anti-inflammatory and for the treatment of diseases of the respiratory tract, rheumatic and muscular pains and gastric ulcer.

Aim Of The Study: To evaluate the effects of fixed oil of Caryocar coriaceum (FOCC) on the topical inflammation and cutaneous wound healing.