Publications by authors named "Maria Leon-Roux"
Background: A World Health Organization (WHO) and International Labour Organization (ILO) systematic review reported sufficient evidence for higher risk of non-melanoma skin cancer (NMSC) amongst people occupationally exposed to solar ultraviolet radiation (UVR). This article presents WHO/ILO Joint Estimates of global, regional, national and subnational occupational exposures to UVR for 195 countries/areas and the global, regional and national attributable burdens of NMSC for 183 countries, by sex and age group, for the years 2000, 2010 and 2019.
Methods: We calculated population-attributable fractions (PAFs) from estimates of the population occupationally exposed to UVR and the risk ratio for NMSC from the WHO/ILO systematic review.
Article Synopsis
- * A significant number of differentially methylated positions (6,796) and regions (866) were identified, indicating that tumor cells exhibited a notable increase in hypermethylation, particularly in gene promoter and body regions.
- * The research highlights three key genes with consistent methylation differences that could serve as potential biomarkers for ESCC, suggesting that these findings could lead to further exploration of DNA methylation's role in cancer diagnosis and treatment.
Background & Aims: There has been consistent evidence for a relationship between smoking and colorectal cancer (CRC), although it is not clear whether the colon or rectum is more sensitive to the effects of smoking. We investigated the relationships between cigarette smoking and risk of CRC and tumor location.
Methods: We analyzed data from 465,879 participants in the European Prospective Investigation into Cancer and Nutrition (EPIC) study; 2741 developed CRC during the follow-up period (mean, 8.