Publications by authors named "Maria Leila M Doquenia"
Background: There are currently seven coronaviruses that can infect humans and the latest addition to these viruses is the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). Infection by SARS-CoV-2 is known commonly as coronavirus disease 2019 (COVID-19). Aside from common manifestations of cough and fever, neurologic symptoms such as headache, disturbed consciousness, paresthesia, and seizures have also been seen.
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- X-linked dystonia-parkinsonism (XDP) is a movement disorder prevalent in the Philippines, predominantly studied in specific regions like Panay Island, but other areas like Mindanao may show different traits.* -
- This study focused on 27 XDP patients in southern Mindanao to explore clinical features and how age at onset (AAO) varies based on genetic factors.* -
- The results indicated a strong correlation between a specific genetic marker and AAO, suggesting the model used can accurately predict the onset age using these genetic modifiers.*
Background: Until recently, about three-quarters of all monogenic Parkinson's disease (PD) studies were performed in European/White ancestry, thereby severely limiting our insights into genotype-phenotype relationships at a global scale.
Objective: To identify the multi-ancestry spectrum of monogenic PD.
Methods: The first systematic approach to embrace monogenic PD worldwide, The Michael J.
Until recently, about three-quarters of all monogenic Parkinson's disease (PD) studies were performed in European/White ancestry, thereby severely limiting our insights into genotype-phenotype relationships at global scale. The first systematic approach to embrace monogenic PD worldwide, The Michael J. Fox Foundation Global Monogenic PD (MJFF GMPD) Project, contacted authors of publications reporting individuals carrying pathogenic variants in known PD-causing genes.
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