Publications by authors named "Maria Laura Artesiani"
Article Synopsis
- During the COVID-19 outbreak, Emergency Departments experienced overcrowding, prompting the need for a simple tool called the ROX index to help in clinical decision-making regarding patient hospitalization and mortality.
- A study at Sant'Orsola-Malpighi Hospital in Italy evaluated the ROX index in 554 COVID-19 patients, finding that a ROX index value below 25.7 indicated a higher likelihood of hospitalization, while a value under 22.3 was linked to increased 30-day mortality.
- Results showed that the ROX index was effective in predicting hospitalization needs, mechanical ventilation requirements, and mortality risk, suggesting its usefulness alongside other clinical assessments.
Proton pump inhibitors are among the most commonly prescribed classes of drugs, and their use is increasing, in particular for long-term treatment, often being over-prescribed and used for inappropriate conditions. In recent years, considerable attention has been directed towards a wide range of adverse effects, and even when a potential underlying biological mechanism is plausible, the clinical evidence of the adverse effect is often weak. Several long-term side effects have been investigated ranging from interaction with other drugs, increased risk of infection, reduced intestinal absorption of vitamins and minerals, and more recently kidney damage and dementia.
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