Effect of phospholipase A inhibitors during infection caused by .

Background: Lipid metabolites play an important role in parasite differentiation and virulence. Studies have revealed that sp. uses prostaglandins to evade innate barriers, thus enabling the parasites to survive inside immune cells.

Leishmania (Viannia) shawi purified antigens confer protection against murine cutaneous leishmaniasis.

Objective: Leishmania (Viannia) shawi was characterized only recently, and few studies concerning the immunogenic and protective properties of its antigens have been performed. The present study aimed to evaluate the protective potential of the five antigenic fractions isolated from L. (V.