Publications by authors named "Maria Kostyleva"
Article Synopsis
- Sebelipase alfa is used to treat lysosomal acid lipase deficiency (LAL-D) and was evaluated in a study to assess its efficacy and safety in patients over a 144-week period.
- Thirty-one patients received sebelipase alfa intravenously, with dose adjustments based on tolerance, and showed significant improvements in liver function, cholesterol levels, and overall health indicators over the study duration.
- The treatment was generally well-tolerated, with mostly mild side effects, and led to positive outcomes in liver histopathology and lipid profiles.