Objective: This study aimed to investigate whether there is a correlation between pathological occlusal changes and the signs and symptoms of temporomandibular dysfunction (TMD).
Methods: This cross-sectional, quantitative, non-randomized clinical trial was conducted on 150 participants. We examined adult patients of both genders with occlusal interference, malocclusion and dental absence in the posterior region of the dental arch that were associated or not associated with painful symptoms.