Does temporal irregularity drive prediction failure in schizophrenia? temporal modelling of ERPs.

Schizophrenia subjects often suffer from a failure to properly predict incoming inputs; most notably, some patients exhibit impaired prediction of the sensory consequences of their own actions. The mechanisms underlying this deficit remain unclear, though. One possible mechanism could consist in aberrant predictive processing, as schizophrenic patients show relatively less attenuated neuronal activity to self-produced tones, than healthy controls.