Publications by authors named "Maria Kandi"
Article Synopsis
- The study examines how early treatment responses impact the outcomes for patients with locally advanced non-small cell lung cancer (LA-NSCLC) receiving concurrent chemo-radiotherapy (cCRT), focusing specifically on the effects of induction chemotherapy (iCX) on patterns of failure (PoF).
- Researchers analyzed data from 276 patients to identify correlations between treatment response metrics—such as tumor volume and SUVpeak—and the likelihood of loco-regional or distant failures.
- Results indicated that squamous cell carcinoma (SCC) patients were more likely to experience loco-regional failures, whereas non-SCC patients had a higher risk of distant failures; also, higher SUVpeak values and poor tumor volume response were linked to increased failure risk.
Background: Adenocarcinoma (AC) and squamous cell carcinoma (SCC) are the most frequent histological subtypes of non-small cell lung cancer (NSCLC). The aim of this study was to investigate how patients with AC and SCC benefit from image-guided adaptive radiotherapy (ART) with tumour match.
Material And Methods: Consecutive patients diagnosed with AC or SCC of the lung treated with definitive chemo-radiotherapy before and after the implementation of ART and tumour match were retrospectively included for analyses.
Introduction: Tumor match and adaptive radiotherapy based on on-treatment imaging increases the precision of RT. This allows a reduction of treatment volume and, consequently, of the dose to organs at risk. We investigate the clinical benefits of tumor match and adaptive radiotherapy for a cohort of non-small cell lung cancer patients (NSCLC).
View Article and Find Full Text PDFIntroduction: Minimizing the planning target volume (PTV) while ensuring sufficient target coverage during the entire respiratory cycle is essential for free-breathing radiotherapy of lung cancer. Different methods are used to incorporate the respiratory motion into the PTV.
Material And Methods: Fifteen patients were analyzed.
Background: The survival rates for patients with non-small cell lung cancer (NSCLC) may be improved by dose escalation; however, margin reduction may be required in order to keep the toxicity at an acceptable level. In this study we have investigated the dosimetric impact of tumor motion and anatomical changes during intensity-modulated radiotherapy (IMRT) of patients with NSCLC.
Material And Methods: Sixteen NSCLC patients received IMRT with concomitant chemotherapy.