Background: Glioblastoma is an incurable neoplasm. Its hypoxia mechanism associated with cancer stem cells (CSCs) demonstrates hypoxia-inducible factor 1α (HIF-1α) expression regulation, which is directly related to tumor malignancy. The aim of this study was to identify a possible tumor malignancy signature associated with regulation of HIF-1α by microRNAs miR-21 and miR-326 in the subpopulation of tumor stem cells which were irradiated by ion in primary culture of patients diagnosed with glioblastoma.
View Article and Find Full Text PDFThe present research aimed to study the chemical composition and acaricidal activity of and essential oils against the cattle tick . GC-MS analysis of essential oil showed limonene (50.3%), -pinene (14.
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