Flexed-knee gait in children with cerebral palsy: a 10-year follow-up study.

Background: While several studies have evaluated the short-term effectiveness of conservative and surgical treatment of flexed-knee gait in children with cerebral palsy (CP), few have explored the long-term outcomes using gait analysis. The purpose of this study was to examine, through gait analysis, the 10-year outcomes of flexed-knee gait in children with CP.

Methods: Ninety-seven children with spastic CP who walked with a flexed-knee gait underwent two gait evaluations [age 6.

Clinical epidemiologic characterization of orthopaedic and neurological manifestations in children with leukodystrophies.

Background: Leukodystrophies (LKDs) are spectra of clinical conditions characterized primarily by brain white matter abnormalities. Although this condition was previously defined around inherited disorders of the white matter of the brain, current application includes acquired and sporadic conditions and some rare conditions that affect gray matter. Over the past 2 decades, information had become available on the clinical subtypes due to neurodiagnostic imaging and improvement in the genetic studies (cytogenetics and molecular genetics) of LKD.