Cortical Frontoparietal Network Dysfunction in -Frontotemporal Dementia.

A rare cause of inherited frontotemporal dementia (FTD) is a mutation in the gene on chromosome 3 leading to the autosomal dominantly inherited FTD (-FTD). Since -FTD is clinically well-characterized, and patients show a distinct pattern of executive dysfunction, the condition offers possible insight in the early electroencephalographic (EEG) changes in the cortical networks. Specifically, EEG microstate analysis parses the EEG signals into topographies believed to represent discrete network activations.