Publications by authors named "Maria Josefina Iglesias"
Front Microbiol
April 2022
Article Synopsis
- The study examined the activity of ADP-glucose pyrophosphorylase (ADP-Glc PPase) from various bacteria regarding its interaction with glucosamine (GlcN) metabolites as substrates or allosteric regulators.
- The enzyme from actinobacteria showed a strong sensitivity to activation by GlcN-6P and was unique in this response compared to other bacterial groups, which exhibited only modest effects.
- Findings highlighted a significant preference for glucose-1-phosphate (Glc-1P) over glucosamine-1-phosphate (GlcN-1P) as a substrate, suggesting evolutionary adaptations in certain bacteria that may enhance their ability to metabolize GlcN, while also providing insights
