Publications by authors named "Maria Jose Vandakunnel"
Article Synopsis
- Fluoroquinolone resistance poses a significant challenge in treating Multidrug-Resistant Tuberculosis (MDR-TB), with notable resistance rates of 33% in MDR-TB and 16.5% in Rifampicin-Resistant TB.
- The most common mutation linked to fluoroquinolone resistance was found in the gyrA gene, specifically D94G, and there was a notable prevalence of pre-XDR-TB and Extensively Drug-Resistant TB among MDR-TB isolates.
- The study emphasizes the urgent need for rapid diagnosis of fluoroquinolone resistance to improve treatment outcomes and control resistance spread in high-prevalence areas.
