Publications by Maria Johanna Pena

Publications by authors named "Maria Johanna Pena"

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Frequency of Gene Polymorphisms in Admixed Venezuelan Women with Recurrent Pregnancy Loss: Microsomal Epoxy Hydroxylase (rs1051740) and Enos (rs1799983).

María Johanna Peña Claudia Valentina De Sanctis Juan Bautista De Sanctis Jenny Valentina Garmendia

Curr Issues Mol Biol

April 2024

Article Synopsis

* The study investigates genetic links to primary RPL by analyzing two specific gene SNPs, rs1051740 (related to detoxification) and rs1799983 (related to blood vessel function), in a case-control format involving 63 RPL patients and 50 controls.
* Results showed a significantly higher frequency of mutated SNP alleles in RPL patients compared to controls, suggesting these genetic polymorphisms may play a role in primary RPL within the Venezuelan admixed

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Fenretinide favorably affects mucins (MUC5AC/MUC5B) and fatty acid imbalance in a manner mimicking CFTR-induced correction.

Dušan Garić Juan B De Sanctis Daciana Catalina Dumut Juhi Shah Maria Johanna Peña

Biochim Biophys Acta Mol Cell Biol Lipids

February 2020

Cystic fibrosis (CF) is the most common genetic disease in Caucasians. CF is manifested by abnormal accumulation of mucus in the lungs, which serves as fertile ground for the growth of microorganisms leading to recurrent infections and ultimately, lung failure. Mucus in CF patients consists of DNA from dead neutrophils as well as mucins produced by goblet cells.

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