Publications by authors named "Maria Jesus Pina"
Background: Drug delivery systems that are able to control the release of bioactive molecules and designed to carry drugs to target sites are of particular interest for tissue therapy. Moreover, systems comprising materials that can respond to environmental stimuli and promote self-assembly and higher order supramolecular organization are especially useful in the biomedical field. Objetive: This review focuses on biomaterials suitable for this purpose and that include elastin-like recombinamers (ELRs), a class of proteinaceous polymers bioinspired by natural elastin, designed using recombinant technologies.
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- Elastin-like polymers and elastin-like recombinamers are special materials used for delivering medicine in new ways.
- They are really good for our body and can work with other materials to create controlled drug-release systems.
- Uses include treating cancer, making tiny carriers for drugs, and creating gels for placing inside the body to release medicine over time.
This report examines the effect of FK506 pretreatment on liver insulin receptor expression in partially (70%) hepatectomized rats. FK506 pretreatment led to an increased insulin receptor number 24 hours after hepatectomy, detected by means of insulin binding and cross-linking procedures. This increase was related to enhanced insulin receptor expression determined by in vitro mRNA translation and Western blot techniques.
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