Publications by authors named "Maria Janieire de N N Alves"

Aims: Although cardiac resynchronization therapy (CRT) improves functional capacity in heart failure patients, a blunted heart rate (HR) response remains after treatment. So we aimed to evaluate the feasibility of the physiological pacing rate (PPR) in CRT patients.

Methods: A cohort of 30 clinical mildly symptomatic CRT patients underwent the six-minute walk test (6MWT).

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Purpose: Endomyocardial fibrosis (EMF) is a restrictive cardiomyopathy associated with low functional capacity and high mortality rates. Exercise training has been proved to be a nonpharmacological treatment of cardiovascular diseases. Therefore, the purpose of this study was to determine the effects of exercise rehabilitation in EMF patients.

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Article Synopsis
  • Patients with obstructive sleep apnea (OSA) experience reduced muscle metaboreflex control of sympathetic nerve activity, but exercise training can improve this in heart failure patients.
  • A study was conducted with 41 OSA patients split into trained (OSAT) and non-trained (OSANT) groups to assess the effects of exercise on muscle sympathetic nerve activity (MSNA).
  • Results showed that exercise training decreased baseline MSNA and increased blood flow, significantly enhancing MSNA responses during muscle ischemia compared to the non-trained group.
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Background: Endomyocardial fibrosis (EMF) is a rare disease, characterized by diastolic dysfunction which leads to reduced peak oxygen consumption (VO2). Cardiopulmonary exercise testing (CPET) has been proved to be a fundamental tool to identify central and peripheral alterations. However, most studies prioritize peak VO2 as the main variable, leaving aside other important CPET variables that can specify the severity of the disease and guide the clinical treatment.

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