Recent Update on the Protective Potentials of Resveratrol against Cisplatin-induced Ototoxicity: A Systematic Review.

Introduction: Although cancer treatment with cisplatin is effective, dose-dependent adverse effects such as ototoxicity occurs often, which limits its clinical use. The use of resveratrol may alleviate the cisplatin-induced ototoxic effects. This study is aimed to review the potential otoprotective effects of resveratrol against cisplatin-induced ototoxicity.

Evaluation of Cholesterol Thickness of Blood Vessels Using Photoacoustic Technology.

One of the primary indicators of plaque vulnerability is the lipid composition of atherosclerotic plaques. Therefore, the medical industry requires a method to evaluate necrotic nuclei in atherosclerosis imaging with sensitivity. In this regard, photoacoustic imaging is a plaque detection method that provides chemical information on lipids and cholesterol thickness in the arterial walls of the patient.

Pathogenic role of 25-hydroxycholesterol in cancer development and progression.

Cholesterol is an essential lipid that serves several important functions, including maintaining the homeostasis of cells, acting as a precursor to bile acid and steroid hormones and preserving the stability of membrane lipid rafts. 25-hydroxycholesterol (25-HC) is a cholesterol derivative that may be formed from cholesterol. 25-HC is a crucial component in various biological activities, including cholesterol metabolism.

Correction: Recent advances on the electrochemical and optical biosensing strategies for monitoring microRNA-21: a review.

Correction for 'Recent advances on the electrochemical and optical biosensing strategies for monitoring microRNA-21: a review' by Amir Abbas Esmaeilzadeh , , 2022, , 4449-4459, https://doi.org/10.1039/D2AY01384C.

The impact of aerosol box on tracheal intubation during the COVID-19 pandemic: a systematic review.

Introduction: This study aimed to summarize the effect of the aerosol box on tracheal intubation in patients with COVID-19.

Areas Covered: According to the PRISMA guidelines, a systematic search was performed to identify relevant literature on the 'impact of the aerosol box on tracheal intubation during the COVID-19 pandemic' in different electronic databases up to March 2021. Based on a set of predefined inclusion and exclusion criteria, 447 articles were screened.

Recent advances on the electrochemical and optical biosensing strategies for monitoring microRNA-21: a review.

The small non-coding RNA, microRNA-21 (miR-21), is dysregulated in various cancers and can be considered an appropriate target for therapeutic approaches. Therefore, the detection of miR-21 concentration is important in the diagnosis of diseases. Low specificity and the cost of materials are two necessary limitations in the traditional diagnosis method such as RT-PCR, northern blotting and microarray analysis.

Concanavalin A as a promising lectin-based anti-cancer agent: the molecular mechanisms and therapeutic potential.

Concanavalin A (ConA), the most studied plant lectin, has been known as a potent anti-neoplastic agent for a long time. Since initial reports on its capacity to kill cancer cells, much attention has been devoted to unveiling the lectin's exact molecular mechanism. It has been revealed that ConA can bind to several receptors on cancerous and normal cells and modulate the related signaling cascades.

Neuroprotective and Anti-Inflammatory Effects of Pioglitazone on Parkinson's Disease: A Comprehensive Narrative Review of Clinical and Experimental Findings.

Parkinson's disease (PD) is a chronic and progressive neurological disorder characterized by the degeneration of dopaminergic neurons in the substantia nigra pars compacta (SNc). The pathogenesis of PD is strongly related to mitochondrial dysfunction, oxidative stress, and neuroinflammation. This indicates that PD can be treated with anti-oxidative substitutes and anti-inflammatory compounds.

Source, toxicity and carcinogenic health risk assessment of heavy metals.

Heavy metals are chemical elements with unique properties that are toxic even in low concentrations and affect human health with different functions. Agricultural and industrial activities, improper disposal of household solid waste and residues related to industrial producers, discharge of household wastewater and agricultural fertilizers are the most important ways in which toxic heavy metals enter the environment, which harms human health and life. A narrative review of the literature was done from 2000 to 2022 based on searched databases included Google Scholar, PubMed, Springer, Web of Science, and Science Direct (Scopus).

Roles of CCR10/CCL27-CCL28 axis in tumour development: mechanisms, diagnostic and therapeutic approaches, and perspectives.

Cancer is now one of the major causes of death across the globe. The imbalance of cytokine and chemokine secretion has been reported to be involved in cancer development. Meanwhile, CC chemokines have received considerable interest in cancer research.

RETRACTED: The pathogenicity of COVID-19 and the role of pentraxin-3: An updated review study.

This article has been retracted: please see Elsevier Policy on Article Withdrawal (https://www.elsevier.com/about/policies/article-withdrawal).

Optical and Electrochemical Aptasensors Developed for the Detection of Alpha-Fetoprotein.

Early diagnosis of hepatocellular carcinoma (HCC), a leading cause of cancer mortality, is decisive for successful treatment of this type of cancer and increasing the patients' survival rate. Alpha-fetoprotein (AFP) is a glycoprotein that has been currently employed as a potential serological biomarker for determination of HCC and several other cancers. Achieving highly sensitive and specific detection of this biomarker is an effective strategy to inhibit developing issues caused by the cancer.

Type 2 alveolar epithelial cell-derived circulating extracellular vesicle-encapsulated surfactant protein C as a mediator of cardiac inflammation in COVID-19.

Among the countless endeavours made at elucidating the pathogenesis of COVID-19, those aimed at the histopathological alterations of type 2 alveolar epithelial cells (AT2) are of outstanding relevance to the field of lung physiology, as they are the building blocks of the pulmonary alveoli. A merit of high regenerative and proliferative capacity, exocytotic activity resulting in the release of extracellular vesicles (EVs) is particularly high in AT2 cells, especially in those infected with SARS-CoV-2. These AT2 cell-derived EVs, containing the genetic material of the virus, might enter the bloodstream and make their way into the cardiovascular system, where they may infect cardiomyocytes and bring about a series of events leading to heart failure.

Optimization of doubly-fed induction generator (DFIG)based wind turbine to achieve maximum power generation with imperialist competitive algorithm (ICA).

Today, due to the end of fossil fuels and efforts to reduce the use of renewable resources, wind energy is a suitable option for the production of electrical energy due to its high-power generation. To increase the output efficiency of wind turbines, maximum power point tracking techniques are required for wind turbine energy conversion systems. In this research, the maximum power point (MPPT) method for two-way fed wind turbine systems (DFIG) is presented.

Electrospun Ta-MOF/PEBA Nanohybrids and Their CH Adsorption Application.

For the first time, biocompatible and biodegradable Ta-metal organic framework (MOF)/polyether block amide (PEBA) fibrous polymeric nanostructures were synthesized by ultrasonic and electrospinning routes in this study. The XRD peaks of products were wider, which is due to the significant effect of the ultrasonic and electrospinning methods on the final product. The adsorption/desorption behavior of the nanostructures is similar to that of the third type of isotherm series, which showed mesoporous behavior for the products.

Neuroprotective and Anti-inflammatory Effects of Pioglitazone on Traumatic Brain Injury.

Traumatic brain injury (TBI) is still a major cause of concern for public health, and out of all the trauma-related injuries, it makes the highest contribution to death and disability worldwide. Patients of TBI continue to suffer from brain injury through an intricate flow of primary and secondary injury events. However, when treatment is provided in a timely manner, there is a significant window of opportunity to avoid a few of the serious effects.

The emerging role of microbiota-derived short-chain fatty acids in immunometabolism.

The accumulating evidence revealed that microbiota plays a significant function in training, function, and the induction of host immunity. Once this interaction (immune system-microbiota) works correctly, it enables the production of protective responses against pathogens and keeps the regulatory pathways essential for maintaining tolerance to innocent antigens. This concept of immunity and metabolic activity redefines the realm of immunometabolism, paving the way for innovative therapeutic interventions to modulate immune cells through immune metabolic alterations.

Prediction of COVID-19 manipulation by selective ACE inhibitory compounds of root: study and ADMET profile.

In the novel SARS-CoV-2 (COVID-19) as a global emergency event, the main reason of the cardiac injury from COVID-19 is angiotensin-converting enzyme 2 (ACE2) targeting in SARS-CoV-2 infection. The inhibition of ACE2 induces an increase in the angiotensin II (Ang II) and the angiotensin II receptor type 1 (AT1R) leading to impaired cardiac function or cardiac inflammatory responses. The ethyl acetate fraction of L.

Conductive Gels: Properties and Applications of Nanoelectronics.

Conductive gels are a special class of soft materials. They harness the 3D micro/nanostructures of gels with the electrical and optical properties of semiconductors, producing excellent novel attributes, like the formation of an intricate network of conducting micro/nanostructures that facilitates the easy movement of charge carriers. Conductive gels encompass interesting properties, like adhesion, porosity, swelling, and good mechanical properties compared to those of bulk conducting polymers.

Psychometric Assessment of the Persian Translation of the Interpersonal Mindfulness Scale With Undergraduate Students.

Interpersonal mindfulness is a construct that significantly contributes to social interaction. To date, no validated measure assessing interpersonal mindfulness has been developed in Iran. Therefore, the aim of this study was to translate and validate the Interpersonal Mindfulness Scale (IMS) among Iranian undergraduate students.